Case library
Practice on real cases
Every case here is adapted from a published case report. The patient is invented; the story, the findings and the test results follow the report. Take the history and find the diagnosis yourself.
250 cases
Cardiology
- Abdominal pain, nausea and vomiting in a 19-year-old manHard
- Central chest pain in a 24-year-old manMedium
- Chest pain after hearing terrible newsEasy
- Chest pain and a racing heart in a 64-year-old manMedium
- Chest pain in a 29-year-old manHard
- Chest pain with ongoing diarrheaEasy
- Chest pressure and lightheadedness in a 53-year-old manMedium
- Chest tightness and shortness of breath in a 17-year-old boyMedium
- Collapse while running in a 17-year-old boyHard
- Dizziness and collapse in a 78-year-old manHard
- Episodes of a sudden racing heartEasy
- Exertional chest pain, near-fainting and tirednessEasy
- Fever, breathlessness and a swollen knee in a young manEasy
- Low back pain going down the right leg in a 47-year-old manHard
- Nausea, vomiting and dizziness in a 76-year-old manMedium
- Painful, discolored toes in a 20-year-old manHard
- Severe chest pain in a 48-year-old womanMedium
- Sharp chest pain worse on breathing inEasy
Pulmonology
- Cough and chest pain for a year in a 41-year-old manHard
- Cough and getting more breathless in a 76-year-old womanMedium
- Cough with blood-streaked sputum in a 13-year-old boyMedium
- Cough, wheeze and fast breathing in a 9-month-old girlMedium
- Dry cough and breathlessness in a 26-year-old manHard
- Dry cough and shortness of breath in a 74-year-old womanHard
- Fainting and breathlessness the day after surgery in a 37-year-old womanMedium
- Fever and shortness of breath in an 18-year-old manHard
- Fever, breathlessness and aching musclesEasy
- Low back and leg pain in a 35-year-old manHard
- Painful red lumps on the shins and a sore breastEasy
- Shortness of breath in a 44-year-old manMedium
- Sudden chest pain in a young womanEasy
- Three months of dry cough triggered by strong smellsEasy
- Tiredness and night sweats in a 28-year-old manMedium
- Worsening asthma control in an 11-year-old boyHard
- Worsening shortness of breath in a 51-year-old manEasy
Gastroenterology
- Abdominal pain after eating in a 57-year-old manMedium
- Abdominal pain and weight loss with a mass in the right lower abdomenEasy
- Abdominal pain around the belly button in a 32-year-old manHard
- Abnormal liver tests for two years in a 47-year-old manMedium
- Bloody diarrhea and crampy abdominal pain in a 30-year-old womanHard
- Colicky upper abdominal pain with jaundiceEasy
- Fever and right upper abdominal painEasy
- Itching all over in a 37-year-old womanMedium
- Painful swollen knuckles and tiredness in a 56-year-old manHard
- Right lower abdominal pain in a 17-year-old boyMedium
- Right lower abdominal pain in a 71-year-old womanMedium
- Right-sided belly pain the day after a bowel testEasy
- Severe upper abdominal pain going through to the backEasy
- Sudden abdominal pain and vomiting in a 25-year-old womanHard
- Ten days of watery diarrheaEasy
- Upper abdominal pain and fevers in a 38-year-old womanHard
- Vomiting and fullness after eating in a 26-year-old womanHard
- Yellow eyes and loss of appetite in an 18-year-old womanMedium
Neurology
- Attacks of severe headacheEasy
- Confusion and not speaking in a 57-year-old womanMedium
- Double vision and trouble swallowingEasy
- Double vision in a 51-year-old manHard
- Drooping right eyelid and unresponsiveness in a 78-year-old manHard
- Drowsiness, confusion and right-sided weaknessEasy
- Episodes of right leg weakness and right hand shaking in a 34-year-old womanHard
- Headache and blurred vision in a 29-year-old manMedium
- Headache with right-sided weakness in a 24-year-old womanMedium
- Inability to move the eyes sideways in a 16-year-old girlMedium
- Severe headache after childbirthEasy
- Severe headache in a 51-year-old womanHard
- Severe one-sided headache with vertigo and vomiting in a 36-year-old womanHard
- Sleepy all the time and can't keep her eyes open in a 39-year-old womanHard
- Sudden loss of speech in a 7-year-old boyMedium
- Sudden weakness of the right arm and leg in late pregnancy in a 22-year-old womanMedium
- Weak legs three weeks after a cesareanEasy
- Weakness of the left side of the faceEasy
Endocrinology
- Confusion and a swollen belly in a 60-year-old manMedium
- Crushing chest pain in a 55-year-old manHard
- Exhaustion and dizziness in a 45-year-old womanHard
- Extreme thirst and passing lots of urineEasy
- Fatigue and muscle weakness in a 63-year-old womanMedium
- Fatigue and swelling in a 90-year-old manHard
- Found confused and cold at homeEasy
- Found unresponsive at homeEasy
- Heat intolerance, sweating and palpitationsEasy
- Nausea, belly pain and tiredness in a 78-year-old womanHard
- No periods and excess hair in a 36-year-old womanMedium
- Painful neck in a 27-year-old womanMedium
- Progressive shortness of breath and swelling in a 54-year-old womanMedium
- Recurrent kidney stonesEasy
- Sudden weakness of the right arm and leg in a 48-year-old manHard
- Two blackouts with shaking in a 20-year-old manHard
- Vomiting, diarrhea and dizziness in a 51-year-old manMedium
- Weight gain, acne and excess hairEasy
Nephrology
- Aching muscles and weak legs in a 70-year-old manMedium
- Blurry vision and red, painful eyes in a 24-year-old manHard
- Cola-colored urine and passing little urine in a boyEasy
- Episode of muscle weakness in a 39-year-old manMedium
- Fast breathing and no urine in a small childEasy
- Fever, left flank pain and red urine in a 25-year-old womanHard
- Frothy urine and leg swelling in a 79-year-old manHard
- Generalized swelling and weight gain in an 81-year-old manMedium
- Muscle cramps and leg weakness in a 20-year-old womanMedium
- Muscle pain and weakness in a 75-year-old manHard
- Progressive leg swelling and frothy urineEasy
- Puffy face and swollen legs with dark urineEasy
- Sudden weakness of all four limbs in a 15-year-old boyMedium
- Swollen legs in a 50-year-old womanHard
- Vomiting, diarrhea and strange visions in an older manEasy
- Vomiting, diarrhea and weakness in a 64-year-old womanMedium
- Weakness in both legs in an 83-year-old manEasy
- Weakness of all four limbs in a 38-year-old womanHard
Rheumatology
- A burst, painful lump on the big toeEasy
- Arm pain and tiredness in a 48-year-old womanMedium
- Blurred vision and recurring mouth soresEasy
- Breathlessness and a new rash in hospital in a 30-year-old womanMedium
- Breathlessness and coughing up blood in a 19-year-old womanHard
- Chest pain and coughing up blood in a 22-year-old manMedium
- Daily high fevers with joint pains and a rash in a 36-year-old womanMedium
- Itchy rash and weak musclesEasy
- Jerky, dance-like movements in an 11-year-old girlHard
- Joint pains and unable to walkEasy
- Painful, stiff small joints of the hands and feetEasy
- Sharp right-sided chest pain and cough in a 45-year-old manHard
- Sudden painful left hip in a 55-year-old manMedium
- Swollen, painful joints and fever in a 41-year-old manHard
- Ten weeks of fever in a 58-year-old womanHard
- Three months of watery diarrhea in a 71-year-old manHard
- Tingling and weakness of the legs in a 38-year-old womanMedium
- Trouble opening her mouthEasy
Infectious Disease
- Ear pain and a drooping faceEasy
- Ear pain and discharge, now with double vision in an 8-year-old girlMedium
- Fever and a spreading rash in a 31-year-old manMedium
- Fever and yellow eyes in a 23-year-old womanMedium
- Fever for weeks after a trip abroadEasy
- Fevers and jaundice in a 66-year-old womanHard
- High fever, vomiting and a red flush in a 28-year-old womanMedium
- High fevers and increasing breathlessness in a 16-year-old boyHard
- High fevers and rigors in an older manEasy
- Left hip pain and difficulty walking in a 54-year-old womanMedium
- Nausea, vomiting and abdominal pain in a 61-year-old manHard
- Painful lumps on the skin after a holidayEasy
- Painful mouth sores for six weeks in a 15-year-old girlHard
- Recurrent fevers with chills in pregnancy in a 29-year-old womanHard
- Sore throat and refusing to eat in a toddlerEasy
- Sweats, dizziness and loss of taste in a 26-year-old manHard
- Tender plaque on the right knee in a 72-year-old manMedium
- Worsening shortness of breath in a teenagerEasy
Hematology
- Bleeding gums and tiny red spots on the skinEasy
- Bloody diarrhea and abdominal pain in a 70-year-old womanHard
- Blurred vision in both eyes in a 44-year-old womanMedium
- Enlarging bruises on the legs in an 18-year-old womanHard
- Fever and a weak right side two weeks after knee surgeryEasy
- Painful prolonged erection in an 18-year-old manHard
- Purple spots on the skin in a 20-year-old manMedium
- Stomach pain and vomiting in a 23-year-old womanHard
- Sudden shortness of breath in an 85-year-old manMedium
- Swelling and passing little frothy urineEasy
- Tiredness and breathlessness in a young womanEasy
- Tiredness and swollen anklesEasy
- Tiredness, headache and a rash of red spots in a 25-year-old manMedium
- Tiredness, headache and joint aches in an older manEasy
- Unresponsiveness after two weeks of vomiting and diarrhea in a 77-year-old womanHard
- Upper abdominal pain in a 34-year-old manMedium
- Vomiting, abdominal pain and weak arms and legs in a 45-year-old manHard
- Worsening breathlessness in a 77-year-old womanMedium
Emergency Medicine
- A painful blistering rash after a chest infectionEasy
- Agitation and confusion in a 29-year-old manMedium
- Confusion in a 71-year-old manHard
- Feeling unwell and confused in a 59-year-old womanMedium
- Flushing, palpitations and a burning mouth after dinner in a 44-year-old womanMedium
- Found drowsy and frothing at the mouthEasy
- Found unconscious at homeEasy
- Found unresponsive at homeEasy
- Headache, vomiting and chest heaviness in a 23-year-old manHard
- Seizure and unresponsiveness in a 20-year-old manHard
- Seizure at a music festival in a 24-year-old manMedium
- Slurred speech and clumsiness after a nap in a 66-year-old manHard
- Sudden severe chest painEasy
- Sudden severe chest pain in a 46-year-old manMedium
- Swollen lips and hives in a 27-year-old manHard
- Vaginal bleeding in a 6-year-old girlHard
- Vomiting, diarrhea and weakness in a 78-year-old womanMedium
- Weakness and drowsiness in a woman with lung cancerEasy
Psychiatry
- Agitated and not sleepingEasy
- Confusion and fever in a 29-year-old womanMedium
- Headache, confusion and odd behavior in a 45-year-old manHard
- Hearing voices and feeling talked about in a 64-year-old womanHard
- Low mood and thoughts of suicideEasy
- Mutism and immobility with fever in a 20-year-old womanHard
- Odd beliefs and agitation in a 44-year-old womanMedium
- Recurrent attacks of jitteriness, palpitations and flushing in a 62-year-old womanHard
- Recurrent fevers and abscesses on the left arm in a 24-year-old womanHard
- Restless and tense for three monthsEasy
- Restlessness and stiff legsEasy
- Silent and unresponsive in a 17-year-old boyMedium
- Strange behavior and confusion in an 11-year-old girlHard
- Sudden confusion on the ward in a 64-year-old womanMedium
- Suddenly stopped speaking in a 66-year-old manMedium
- Two seizures in a man with schizophreniaEasy
- Unsteady walking, shaky hands and slurred speech in a 53-year-old womanMedium
Obstetrics & Gynecology
- A lump coming out of the vagina in a 17-year-old girlHard
- Abdominal swelling and pain in a teenagerEasy
- Bleeding from the belly button in a 35-year-old womanMedium
- Breathless lying flat at 40 weeksEasy
- Colicky left lower abdominal pain in a 36-year-old womanHard
- High fever and right lower abdominal pain after a cesarean in a 33-year-old womanMedium
- Irregular vaginal bleeding in a 54-year-old womanMedium
- Jaundice and passing little urine after delivery in a 33-year-old womanMedium
- Nausea and vomiting in pregnancyEasy
- New acne, excess hair and a deeper voice in pregnancy in a 25-year-old womanMedium
- Painful lump in an operation scarEasy
- Painless spotting in early pregnancyEasy
- Right lower abdominal pain and vomiting in late pregnancy in a 32-year-old womanMedium
- Severe shortness of breath and fainting in pregnancy in a 31-year-old womanHard
- Sudden severe lower abdominal pain in early pregnancy in a 36-year-old womanHard
- Sudden severe right lower abdominal painEasy
- Uncontrolled high blood pressure and vomiting after delivery in a 30-year-old womanHard
- Vomiting, diarrhea and weakness in a 51-year-old womanHard
Pediatrics
- Agitation and confusion after swallowing pillsEasy
- Back pain for two months in a 7-year-old boyMedium
- Blackouts and seizures in a 10-year-old boyMedium
- Bruising and painful swollen legs, unable to walk in a 13-year-old boyHard
- Cough and wheeze that keeps coming back in an 11-year-old boyHard
- Diarrhea and a swollen belly that won't go away in a 3-year-old boyMedium
- Diarrhea and drowsiness in a 6-month-old girlHard
- Failing vision, falls and jerking in a 13-year-old boyHard
- Fever and an itchy rash in a 14-year-old girlMedium
- Fever, rash and yellow skin in a childEasy
- Fever, tiredness and fainting in a girlEasy
- Generalized swelling in a 20-month-old boyHard
- Heel pain and inability to walk in a 9-year-old boyMedium
- High fevers and a rash in a childEasy
- Painful swollen legs in a boyEasy
- Reduced movement of the right arm in a newborn boyHard
- Swollen, purple toes in a babyEasy
- Weakness of the left arm and leg in a 23-month-old boyMedium
Dermatology
- Attacks of severe crampy abdominal pain in a 27-year-old manHard
- Blisters on the hands and dark urine in a 59-year-old manMedium
- Burning, painful tongue in a 45-year-old manHard
- Fever and a spreading rash in a 39-year-old womanMedium
- Itching all over for ten months in a 65-year-old womanHard
- Itchy, crusted scalp sores in an older womanEasy
- Itchy, scaly rash spreading over two weeksEasy
- Painful blistering rash and yellow eyes in a 22-year-old manMedium
- Painful red lumps on the shins with sore jointsEasy
- Painful skin ulcers that keep enlarging in a 26-year-old manMedium
- Persistent fever after leaving hospital in a 52-year-old manHard
- Red skin and blisters in a newbornEasy
- Severely itchy rash that won't go away in a 59-year-old womanMedium
- Throat swelling and difficulty swallowing in a 56-year-old manHard
- Ulcers on both hands that won't heal in a 71-year-old manHard
- Very itchy rash in late pregnancyEasy
- Wavy red rash on a baby's tummyEasy
- Widespread red rash and fever in a 70-year-old womanMedium